cortical spreading depression (csd) has been suggested to underlie some neurological disorders such as migraine. despite the intensity with which many investigators have studied sd in the brain, only a few studies have aimed to identify sd in the spinal cord. here we described the main characteristic features of sd in the spinal cord induced by different methods including various spinal cord in...

acute paraplegia is a rare but catastrophic complication of surgeries performed on aorta and corrective operations of vertebral column. trauma to spinal cord after spinal anesthesia and ischemia of spinal cord also may lead to acute paraplegia. acute paraplegia as a complication of general anesthesia in surgeries performed on sites other than aorta and vertebral column is very rare. here we pre...

abstract   objective: to evaluate and review our experience with pediatric spinal injuries and factors affecting outcome, the authors conducted a retrospective clinical study of 43 cases (32 boys, 11 girls) of pediatric spine injuries treated during four years (january 1999 to december 2003).   methods: forty-three children with spinal injuries were studied retrospectively over four years and w...

compound action potential (cap) of spinal cord represents valuable properties of neural fibers including excitability, rate of myelination and membrane integrity. these properties are measured using amplitude, latency and area under curve of caps recorded from spinal cord. here, the isolated spinal cord was set in a double sucrose gap (dsg) chamber and its response to intracellular stimulation ...

Spinal cord injury is a devastating chronic condition resulting in temporary or permanent motor,sensory or autonomic dysfunction of the cord. The manifestation of spinal cord injury based onthe severity and involved areas could be different. Numerous studies have demonstrated thatbradycardia, hypotension, and orthostatic hypotension are present insignificant number ofpat...

a 60-year-old patient with testicular seminoma was referred for f-18 fdg pet/ct study to evaluate recurrence. in addition to hypermetabolic cervical, mediastinal and hilar lymph node tumoral metastases, segmental intense fdg uptake along the lumbar spinal cord suggestive of tumoral metastasis was noted which quite an unusual presentation is.  at the time of pet study the patient was symptomless...

treatment of spinal cord injury by exogenous cells has brought both successful and unsuccessful results. olfactory ensheathing cells and schwann cells have been widely used for transplantation purposes. in this study, we investigated the effects of these cells on contused spinal cord by introducing cells into subarachnoid space. fifty thousand schwann cells or olfactory ensheathing cells or a m...

objective: spinal cord injury (sci) causes inflammation, deformity and cell loss. it has been shown that melissa officinalis (mo), as herbal medicine, and dexamethasone (dex) are useful in the prevention of various neurological diseases. the present study evaluated combinational effects of dex and mo on spinal cord injury. materials and methods: thirty six adult male wistar rats were used in th...